Monday, January 14, 2008

New Recommendations on Anti-Aging Supplements


Recently I have come across this new book written by a medical doctor for lay public with practical recommendations what supplements to take in order to fight the aging of our brains:

The Brain Trust Program: A Scientifically Based Three-Part Plan to Improve Memory, Elevate Mood, Enhance Attention, Alleviate Migraine and Menopausal Symptoms, and Boost Mental Energy
by Larry McCleary, M.D.

Here is the new suggested anti-aging protocol for taking the following supplements:

Magnesium, 600 mg at bedtime

Taurine, 1 gram each morning and 1 gram each evening

Acetyl L-carnitine, 100-500 mg a day

Alpha-lipoic acid, 50-300 mg a day

Coenzyme Q10, 25-100 mg a day

Vitamin D, 400 IU in oil as a soft gel a day

Huperzine A, 75-100 mcg twice a day

Vinpocetine, 5-10 mg twice a day

Marine lipids:

-- eicosapentaenoic acid (EPA), 1-2 grams per day

-- docosahexaenoic acid (DHA), 1-2 grams per day

-- krill oil, 2-4 capsules per day

B vitamins (daily doses):

-- thiamin (B1), 20 mg

-- riboflavin (B2), 20 mg

-- niacin, 20 mg

-- pantothenic acid, 20 mg

-- biotin, 300 mg

-- pyridoxine (B6), 20 mg

-- cobalamin (B12), 100 mcg

-- folic acid, 800 mcg

-- choline, 20 mg

The book also suggests the so-called "Ketogenic Cocktail" to treat hot flashes in menopausal women:

-- Medium-chain triglycerides (MCT) oil, 1-2 tablespoons (about 15 grams/tablespoon)
-- Flaxseed oil, 1 teaspoon to 1 tablespoon
-- Eicosapentaenoic acid (EPA), 50 mg

It may be interesting to hear from the experts here, whether these supplements would really work, are their doses appropriate, and what side effects may be possible.

To share your knowledge, or perhaps even your personal experience in trying these supplements already, please post you comments below, by clicking here

Thank you!

By the way, this new book is now available at Amazon:

Longevity Science
New Recommendations on Anti-Aging Supplements
Shorter weblink:


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Anonymous Anonymous said...

I would say, this is a conservative regime regarding the following nutrients:

Vitamin D, 400 IU

There are now more recent evidence, that a much higher dose of vitamin D (only vitamin D3 should be used) is necessary, to maintain high enough blood levels to prevent cancer, viral infections, promote healthy immune system, prevent arterial plaque.

2000IU daily is the conservative suggestion, but more may be necessary.

Folic acid should be about 1400ug, to lower Homcystein.

At least 400IU vitamin E (as natural or mixed tocopherols)

and 100ug selenium should be added.

Vitamin K2 as Menaquinone-7 should be added too, as it prevent osteoporosis and arterial plaque.
The lowest working dose is about 45ug, but 100ug should not hurt.

I am not an pro in this field, but this is, what i have learned from many studies and many reliable source of information on the net.
But probably the most important thing for a long& healthy live is to avoid taking prescription med`s as prevention.
This includes ASS, statins and blood thinning agents like warfarine.

3:10 PM  
Blogger Larry said...

This is a comment in response to the "New Recommendations on Anti-Aging Supplements" listed on the Longevity Science Blog. I wrote The Brain Trust Program where these recommendations appear. I would not characterize this combination of nutritional supplements as an anti-aging regimen, but rather as a combination of nutrients that a broad population can safely take for the promotion of brain health.

I fully agree with the anonymous commenter that for a number of reasons the optimal dose of vitamin D3 is about 5000IUs per day. I also agree with the vitamin K2 recommendations (but there is not yet evidence I am aware of that it enhances brain health).

Larry McCleary

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