Monday, February 05, 2007

Steve Spindler


Recently a very clever and eloquent comment was posted at this blog. The author of this comment is Professor Steve Spindler. So I went to Medline to see his scientific publications and was pleased to find out that he has published 49 articles on aging and longevity studies in good scientific jounals. Here is a partial list of his most recent publications:


1: Dhahbi JM, Tsuchiya T, Kim HJ, Mote PL, Spindler SR. Related Articles, Links
Abstract Gene expression and physiologic responses of the heart to the initiation and withdrawal of caloric restriction.
J Gerontol A Biol Sci Med Sci. 2006 Mar;61(3):218-31.
PMID: 16567370 [PubMed - indexed for MEDLINE]

2: Spindler SR. Related Articles, Links
Abstract Use of microarray biomarkers to identify longevity therapeutics.
Aging Cell. 2006 Feb;5(1):39-50.
PMID: 16441842 [PubMed - indexed for MEDLINE]

3: Dhahbi JM, Mote PL, Fahy GM, Spindler SR. Related Articles, Links
Free Full Text Identification of potential caloric restriction mimetics by microarray profiling.
Physiol Genomics. 2005 Nov 17;23(3):343-50. Epub 2005 Sep 27.
PMID: 16189280 [PubMed - indexed for MEDLINE]

4: Spindler SR. Related Articles, Links
Abstract Rapid and reversible induction of the longevity, anticancer and genomic effects of caloric restriction.
Mech Ageing Dev. 2005 Sep;126(9):960-6. Review.
PMID: 15927235 [PubMed - indexed for MEDLINE]

5: Dhahbi JM, Kim HJ, Mote PL, Beaver RJ, Spindler SR. Related Articles, Links
Free in PMC Temporal linkage between the phenotypic and genomic responses to caloric restriction.
Proc Natl Acad Sci U S A. 2004 Apr 13;101(15):5524-9. Epub 2004 Mar 25.
PMID: 15044709 [PubMed - indexed for MEDLINE]

6: Tsuchiya T, Dhahbi JM, Cui X, Mote PL, Bartke A, Spindler SR. Related Articles, Links
Free Full Text Additive regulation of hepatic gene expression by dwarfism and caloric restriction.
Physiol Genomics. 2004 May 19;17(3):307-15.
PMID: 15039484 [PubMed - indexed for MEDLINE]

7: Dhahbi JM, Mote PL, Cao SX, Spindler SR. Related Articles, Links
Abstract Hepatic gene expression profiling of streptozotocin-induced diabetes.
Diabetes Technol Ther. 2003;5(3):411-20.
PMID: 12828825 [PubMed - indexed for MEDLINE]

8: Spindler SR. Related Articles, Links
Abstract Reversing the negative genomic effects of aging with short-term calorie restriction.
ScientificWorldJournal. 2001 Oct 12;1:544-6. Review.
PMID: 12805847 [PubMed - indexed for MEDLINE]

9: Weindruch R, Keenan KP, Carney JM, Fernandes G, Feuers RJ, Floyd RA, Halter JB, Ramsey JJ, Richardson A, Roth GS, Spindler SR. Related Articles, Links
Abstract Caloric restriction mimetics: metabolic interventions.
J Gerontol A Biol Sci Med Sci. 2001 Mar;56 Spec No 1:20-33. Review.
PMID: 12088209 [PubMed - indexed for MEDLINE]

10: Spindler SR. Related Articles, Links
Abstract Calorie restriction enhances the expression of key metabolic enzymes associated with protein renewal during aging.
Ann N Y Acad Sci. 2001 Apr;928:296-304. Review.
PMID: 11795521 [PubMed - indexed for MEDLINE]

It looks like the author is an expert in aging and longevity studies, and therefore his comments should be taken seriously.

Professor Steve Spindler also published book chapters in these scientific books:

Aging of the Organs and Systems
(Biology of Aging and its Modulation)

by Richard Aspinall

Dhahbi, J.M. and Spindler, S.R. Aging of the liver. In, Biology of Aging and its Modulation, Vol. 3: Aging of Organs and Systems , Aspinall, R., ed., Kluwer Academic Publisher, Dordrecht , The Netherlands , pp. 271-291 (2003).

Energy Metabolism and Lifespan Determination (Advances in Cell Aging and Gerontology)
by M.P. Mattson

Spindler, S.R. and Dhahbi, J.M. Protein Turnover, Energy Metabolism, Aging and Caloric Restriction. In, Energy Metabolism and Lifespan Determination: Advances in Cell Aging and Gerontology Vol. 14, Mattson, M.P., ed., Elsevier, Amsterdam , The Netherlands , pp. 69-86 (2003).

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