New Study on Human Aging, Mortality and Longevity

Dear Friends and Colleagues,

We are pleased to share with you the results of our new study, just published by a professional journal Demografie:

Ageing and Longevity:
Mortality Laws and Mortality Forecasts for Ageing Populations
Demografie, 2011, 53(2): 109-128.

Full text is available online at:
http://longevity-science.org/pdf/Demografie-2011.pdf

If you have any difficulty reading Czech, the English translation is available here:

http://longevity-science.org/pdf/Demografie-English-2011.pdf

Abstract:

The increase in the number of people surviving to an advanced age poses a serious challenge to the government pension systems of industrialised societies. Therefore, accurate estimates of mortality at advanced ages are essential to improve forecasts of mortality and the population size of the oldest old age group.

In this article the authors present some new approaches to mortality and population projections at older ages using Swedish period life table data. Using two simple assumptions about age- and time patterns of mortality change (log-linear decline of mortality over time and exponential growth of hazard rates with age up to very advanced ages), the authors made mortality projections for Swedish males and females for the next fifty years.

Keywords:

ageing population, mortality laws, Gompertz-Makeham law, background (component of) mortality, senescent (component of) mortality, mortality at advanced ages, mortality forecast

Comments and suggestions are most welcome!

To read and post comments, click here.

Best wishes,

-- Leonid and Natalia


-------------------------------------------------
-- Leonid Gavrilov, Ph.D., GSA Fellow
-- Natalia Gavrilova, Ph.D., GSA Fellow
Center on Aging, NORC at the University of Chicago
Website: http://longevity-science.org/
Blog: http://longevity-science.blogspot.com/
Our books: http://longevity-science.org/Books.html


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Scientific Meeting in Moscow - “From Homo sapiens to Homo sapiens liberatus”

See also:
-- 'Books Forum' blog
-- 'Health Studies' blog


Dear Friends!

We are pleased to share with you the program of international scientific conference on aging and longevity, which was held at Moscow State University recently (with our participation and presentation there)

You can see the Power-Point-Presentation of our study here:

"Comparative analysis of parameters of human ontogenesis and senescence"

http://longevity-science.org/Ontogenesis-Senescence.ppt

Any comments and suggestions are most welcome!


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Workshop “From Homo sapiens to Homo sapiens liberatus”

25 May

9.15-9.45 Registration, coffee

9.45-12.00 Chairman, D.B. Zorov

9.45-10.00 V.P. Skulachev. Introductory remarks

10.00-10.45 V.P. Skulachev and M.V. Skulachev The present state of the art of SkQ Megaproject

10.45-11.00 Discussion

11.00-11.15 B. Cannon. Effects of SkQ1 on progeric “Mutator mice” (report 1)

11.15-11.30 Discussion

11.30-11.45 J. Nedergaard. Effects of SkQ1 on progeric “Mutator mice” (report 2)

11.45-12.00 Discussion

12.00-12.30 Coffee break

12.30-14.30 Chairmen, B. Cannon, V.I. Kapelko

12.30-12.45 D.B. Zorov. Effects of SkQs on kidney and brain ischemia/reperfusion injuries.

12.45-13.00 Discussion

13.00-13.15 B.V. Chernyak. SkQ1 accelerates dermal wound healing and arrests the age-dependent decline of this process

13.15-13.30 Discussion

13.30-13.45 N.G. Kolosova. Effects of SkQ on cataract and retinopathies in OXYS rats.

13.45-14.00 Discussion

14.00-14.15 A.A. Zamyatnin. Clinical trials of the SkQ1 drops in treatment of “dry eye”

14.15014.30 Discussion

14.30-15.45 Lunch

15.45-17.45 Chairmen, J. Nedergaard, E.I. Rogaev

15.45-16.00 V.N. Anisimov. Effects of SkQ on SHR and HER-2 mice.

16.00-16.15 Discussion

16.15-16.30 F.F. Severin. Two mechanisms of antioxidant activity of SkQs.

16.30-16.45 Discussion

16.45-17.00 D.A. Cherepanov. Possible role of the Complex III bound cardiolipin dimer in initiation of mitochondrial lipid peroxidation

17.00-17.15 Discussion

17.15-17.30 S. A. Nedospasov. Unexpected features in mice with mutant cytochrome c.

17.30-17.45 Discussion

17.45-18.15 Coffee break

18.15-18.30 R. Zinovkin. How counterproductive programs could escape elimination by natural selection?

18.30-18.45 Discussion

18.45-19.00 V. Gorbunova. Naked mole-rat, a rodent lacking the senescence program, in comparison with his senescing relatives.

19.00-19.15 Discussion

19.45-20.15 Chairmen, G. Libertini, L. Gavrilov

19.15-19.30 A. Siluanov. Naked mole-rat, a cancer-resistant animal.

19.30-19.45 Discussion

19.45-20.00 H.S. Saunders. Programmed vs stochastic aging mechanisms.

20.00-20.15 Discussion

26 May

9.30-12.00 Chairmen, J. Mitteldorf, S.A. Nedospasov

9.30-9.45 K. Lewis. Examples of counterproductive genetic programs in prokaryotes.

9.45-10.00 Discussion

10.00-10.15 N. Gavrilova. Comparative analysis of parameters of human ontogenesis and senescence.

10.15-10.30 Discussion

10.30-10.45 G. Libertini. Aging in wild nature.

10.45-11.00 Discussion

11.00-11.15 T. Goldsmith. Biological functions of aging.

11.15-11.30 Discussion

11.30-12.00 Coffee break

12.00-14.00 Chairmen, T. Goldsmith, B.V. Chernyak

12.00-12.15 J. Mitteldorf. Evolvability, a necessary component of biological evolution

12.15-12.30 Discussion

12.30-12.45 C.J. Hauser. Appearance of mitochondrial DNA and formyl methionine in the blood induces programmed death of organism, resembling septic shock.

12.45-13.00 Discussion

13.00-13.30 General discussion

13.30-13.45 A.G. Ryazanov. An enzyme which shortens the lifespan

13.45-14.00 Discussion

14.00-15.30 Lunch

15.30-16.45 Discussion on establishment of the Homo sapiens liberatus (HSL) movement. Chairman V.P. Skulachev

16.45-17.00 Concluding remarks

========================

Abstract of our presentation:

Comparative analysis of parameters of human ontogenesis and senescence

Natalia S. Gavrilova and Leonid A. Gavrilov
Center on Aging, NORC and The University of Chicago

The idea of this study is to compare standard deviations for parameters, which are known to be determined by the developmental program (such as ages of sexual maturity) with variation of characteristics related to aging (such as menopause and death).

One of the arguments used by the opponents of programmed aging is a too high variation in individual lifespans compared to the observed variation of programmed events (such as the age of sexual maturation). The main objective of this study is to test the validity of this argument.

Presentation provides the first results on this topic of scientific studies. In particular, data available in the scientific literature on variability of ages at sexual maturation (menarche), menopause and death are compared to results obtained from the nationally representative survey of adult population of the United States (MIDUS) as well as official life table data.

It is shown that standard deviations for age at onset of menarche are about 10 times smaller than standard deviations for ages of death. Such a difference corresponds well to a difference in mean values of ages when menarche and death occur. Thus, the adjusted variability (coefficient of variation) for age at death is of a similar order of magnitude as that for ages at onset of menarche.

=======================================

Comments and suggestions are welcome!

Home:
Longevity Science Blog
and
Scientific Meeting in Moscow - “From Homo sapiens to Homo sapiens liberatus”
Shorter weblink:
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News on Reliability Theory of Aging and Longevity

See also:
-- 'Books Forum' blog
-- 'Health Studies' blog


Greetings,

Here are some excerpts from the a new interview, which is just published by the scientific journal Rejuvenation Research:

Rejuvenation Research, 2009, 12(5): 371-374.
http://www.liebertonline.com/doi/abs/10.1089/rej.2009.0979
back-up copy:
http://health-studies.org/pdf/Interview-RR-2009.pdf

The excerpts are provided in their original, non-edited form, as they were initially presented before the publication.

Any comments and suggestions are welcome!

Please feel free to post your comments and suggestions below by clicking here.

-- Leonid Gavrilov

---------------------------------
-- Leonid Gavrilov, Ph.D. , GSA Fellow
Center on Aging, NORC/University of Chicago
Website: http://longevity-science.org/
Blog: http://longevity-science.blogspot.com/
Our books: http://longevity-science.org/Books.html

---------------------------------------------------

Excerpts from Interview

Question:

3. You have spearheaded the application of reliability theory to the modeling of aging and mortality. Reliability theory is designed to describe the behavior of man-made machines, which differ from living organisms in that they do not incorporate significant in-built self-repair machinery. To what extent do you feel that this difference diminishes the applicability of reliability theory to living organisms?


Answer:

Thank you for your kind comment on our 'spearheading' . Yes, we first started to apply reliability theory to the problem of biological aging more than 30 years ago, as early as in 1978 [1, 2], and since that time the reliability theory of aging and longevity has become well known in scientific literature [3 - 9]. To answer your question on applicability of reliability theory to living organisms, it is useful to consider separately two different topics: (1) applicability of reliability theory as a general concept; and (2) applicability of our particular mathematical models based on reliability theory.

Discussing the first topic, it is important to note that reliability theory is a general theory about systems failure. It allows researchers to predict the age-related failure kinetics for a system of given architecture (reliability structure) and given reliability of its components. Although historically it was initially applied to describe the behavior of man-made machines, nothing in this general mathematical theory prevents us from taking into account the in-built self-repair machinery, if this is needed. Therefore, there are no fundamental problems with applicability of reliability theory to living organisms, as there are no problems in applicability of mathematics in general to living organisms.

Discussing the second topic, it was our initial intent to find the most simple explanation for the major facts about aging and mortality (the very origin of aging, the Gompertz law of mortality, the compensation law of mortality, and the late-life mortality deceleration). We were interested in understanding the first principles and fundamental explanations of aging, before trying to create a comprehensive model, which takes into account all the complexities of living organisms. Therefore, in our models we were focused on accumulation of un-repaired damage as the final outcome of the damage-vs-repair process, leading to age-related decrease in systems redundancy (e.g. decrease in numbers of functional cells).

Now, when these intentionally simplified models with minimum number of assumptions gave us some general understanding of the nature of aging process and mortality laws, the way is opened to build upon them a more detailed and complex model of aging. This work is opened to everyone who can find a protected time to do it.

Another interesting feature of biological systems is that they are formed in evolution during a severe struggle for survival, and biological arms race with numerous infections and predators. Therefore they have many potentially harmful defense mechanisms, which may be useful for short-term survival in hostile wild environment, but not conductive for longevity in a protected environment (like the inflammation response).

So the analogy between living organisms and man-made machines is more appropriate for a man-made military machines, overloaded by weaponry and ammunition at the expense of their durability. Such machines could last much longer in protected environment if many dangerous fighting devices are removed from them.

The same is true for living organisms -- loss of some functions through introduced mutations or other interventions often leads to increased species longevity in a protected environment. Sometimes this observation is interpreted as a proof that aging is a programmed process, while in fact it simply means that organisms were selected by Nature for survival in the wild hostile environment, rather than for longevity in protected laboratory conditions.


References

1. Gavrilov, L.A. A mathematical model of the aging of animals. Proc. Acad. Sci. USSR [Doklady Akademii Nauk SSSR], 1978, 238(2): 490-492. English translation by Plenum Publ Corp: pp.53-55. PMID 624242

2. Gavrilov, L.A., Gavrilova, N.S., Yaguzhinsky, L.S. The main regularities of animal aging and death viewed in terms of reliability theory. J. General Biology [Zhurnal Obschey Biologii], 1978, 39(5): 734-742. PMID 716614

3. Gavrilov LA, Gavrilova NS. Reliability Theory of Aging and Longevity. In: Masoro E.J. & Austad S.N.. (eds.): Handbook of the Biology of Aging, Sixth Edition. Academic Press. San Diego, CA, USA, 2006, 3-42. ISBN 0-12-088387-2

4. Gavrilov LA, Gavrilova NS. Models of Systems Failure in Aging. In: P Michael Conn (Editor): Handbook of Models for Human Aging, Burlington, MA : Elsevier Academic Press, 2006. 45-68. ISBN 0-12-369391-8.

5. Gavrilov LA, Gavrilova NS. Why We Fall Apart. Engineering's Reliability Theory Explains Human Aging. IEEE Spectrum, 2004, 41(9): 30-35.

6. Gavrilov LA, Gavrilova NS. The Reliability-Engineering Approach to the Problem of Biological Aging. Annals of the New York Academy of Sciences, 2004, 1019: 509-512. PMID 15247076

7. Gavrilov L.A., Gavrilova N.S. The quest for a general theory of aging and longevity. Science's SAGE KE (Science of Aging Knowledge Environment) for 16 July 2003; Vol. 2003, No. 28, 1-10. http://sageke.sciencemag.org , PMID 12867663

8. Gavrilov L.A., Gavrilova N.S. The reliability theory of aging and longevity. Journal of Theoretical Biology, 2001, 213(4): 527-545. PMID 11742523

9. Gavrilov L.A., Gavrilova N.S (1991), The Biology of Life Span: A Quantitative Approach. New York: Harwood Academic Publisher, ISBN 3-7186-4983-7

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Key words:
Reliability Theory of Aging and Longevity, Rejuvenation Research, Reliability Theory of Aging, Interview, Reliability Theory, , Leonid Gavrilov, Natalia Gavrilova, ageing, aging, gerontology, longevity, repair, mortality laws, the origin of aging, the Gompertz law of mortality, the compensation law of mortality, the late-life mortality deceleration


Home:
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Shorter weblink:
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.

New Interview on Aging and Longevity Studies

See also:
-- 'Books Forum' blog
-- 'Health Studies' blog


Greetings,

This is to invite you to comment here on new interview on aging and longevity studies, published recently by the 'Rejuvenation Research' journal:

Rejuvenation Research, 2009, 12(5): 371-374.
http://www.liebertonline.com/doi/abs/10.1089/rej.2009.0979
and:
http://health-studies.org/pdf/Interview-RR-2009.pdf

Any comments and suggestions are welcome!

Please feel free to post your comments and suggestions below by clicking here.

-- Leonid Gavrilov

---------------------------------
-- Leonid Gavrilov, Ph.D. , GSA Fellow
Center on Aging, NORC/University of Chicago
Website: http://longevity-science.org/
Blog: http://longevity-science.blogspot.com/
Our books: http://longevity-science.org/Books.html

P.S.:
Also, here are some excerpts from this published interview (original non-edited text):

1. How, in general, can demographers contribute to the effort to develop medical treatments to combat aging?

There are several ways how human population studies could be very useful for efforts to extend healthy life span.

First, there is an area of biodemography - a science, which integrates biological knowledge with demographic approaches in attempt to understand the dynamics of vital events in human populations, including mortality and longevity [1-4]. Looking back at the history of science we can see that such important health findings as the discovery of long-term harmful effects of smoking, hypertension, high cholesterol levels and hyperglycemia all came from statistical (epidemiological) studies on human populations. These significant findings from population studies served as a guide and justification for subsequent development of specific medical treatments and health policies already saving many human lives now.

Looking forward at the future of biodemographic studies, we anticipate 'unraveling the secrets of human longevity' -- the discovery of determinants for exceptional human survival, which allow some individuals to delay dramatically many diseases of aging, and to live a remarkably healthy long life (sometimes beyond 100 years). When we find out why some people are so resilient to aging, these findings could serve as a guide and justification for development of new medical treatments and health policies to combat aging. To make this happen we developed a new research project 'Biodemography of Exceptional Longevity', which was recently awarded a grant from the U.S. National Institute on Aging, NIA. Information about the progress of this research project is continually updated at our scientific website 'Unraveling the secrets of human longevity' ( http://longevity-science.org/ ), and it is opened for comments and public discussion at our blog 'Longevity Science' ( http://longevity-science.blogspot.com/ ). Some preliminary findings on this topic are already published [5-7].

Second, there is an area of traditional demography, which has tools to make demographic projections for different scenarios of life extension. This is an important issue, because a common objection against starting a large-scale biomedical war on aging is the fear of catastrophic population consequences (overpopulation). This fear is only exacerbated by the fact that no detailed demographic projections for radical life extension scenario were published so far. What would happen with population numbers if aging-related deaths are significantly postponed or even eliminated? Is it possible to have a sustainable population dynamics in a future hypothetical non-aging society? These are important questions, which could be answered through traditional demographic studies.

Recently we made a new study, which explores different demographic scenarios and population projections, in order to clarify what could be the demographic consequences of a successful biomedical war on aging. The results of this study supported by the Methuselah and SENS foundations were presented at the SENS4 conference in Cambridge, UK, this September, and are expected to be published [8]. In brief, we found that defeating aging, the joy of parenting and sustainable population size are not mutually exclusive. This is an important point, because it can change the current public perception that life-extension necessarily leads to overpopulation. Amazingly, when we were returning back to the USA from the SENS4 conference in England, the passport control officer asked us exactly the same question about overpopulation during the interview about the purpose of our international travel! This example indicates how deep is the penetration of overpopulation scare in the fabrics of modern society, and hence how important are the demographic studies on this topic.

References

1. Curtsinger JW, Gavrilova NS, Gavrilov LA. Biodemography of Aging and Age-Specific Mortality in Drosophila melanogaster. In: Masoro E.J. & Austad S.N.. (eds.): Handbook of the Biology of Aging, Sixth Edition. Academic Press. San Diego, CA, USA, 2006, 261-288.

2. Gavrilov L.A., Gavrilova N.S., Olshansky S.J., Carnes B.A. Genealogical data and biodemography of human longevity. Social Biology, 2002, 49(3-4): 160-173.

3. Gavrilov, L.A., Gavrilova, N.S. Biodemographic study of familial determinants of human longevity. Population: An English Selection, 2001, 13(1): 197-222.

4. Gavrilova, N.S., Gavrilov, L.A. Data resources for biodemographic studies on familial clustering of human longevity. Demographic Research [Online], 1999, vol.1(4): 1-48. Available: http://www.demographic-research.org/Volumes/Vol1/4/

5. Gavrilova N.S., Gavrilov L.A. Can exceptional longevity be predicted? Contingencies [Journal of the American Academy of Actuaries], 2008, July/August issue, pp. 82-88.

6. Gavrilova N.S., Gavrilov L.A. Physical and Socioeconomic Characteristics at Young Age as Predictors of Survival to 100: A Study of a New Historical Data Resource (U.S. WWI Draft Cards). Living to 100 and Beyond: Survival at Advanced Ages [online monograph]. The Society of Actuaries, 2008, 23 pages.

7. Gavrilova N.S., Gavrilov L.A. Search for Predictors of Exceptional Human Longevity: Using Computerized Genealogies and Internet Resources for Human Longevity Studies. North American Actuarial Journal, 2007, 11(1): 49-67.

8. Gavrilov L.A., Gavrilova N.S. Demographic Consequences of Defeating Aging. [Meeting Abstract]. Rejuvenation Research, 2009, 12( Suppl. 1): 29-30.

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Key words:
Rejuvenation Research, Interview, Overpopulation, Reliability Theory, Predictors of Exceptional Longevity, Leonid Gavrilov, Natalia Gavrilova, ageing, aging, gerontology, longevity, centenarians, parental age


Home:
Longevity Science Blog
and
New Interview on Aging and Longevity Studies
Shorter weblink:
http://tinyurl.com/ydpnvhe


.

Call to Danish Colleagues

See also:
-- 'Books Forum' blog
-- 'Health Studies' blog


Greetings,

We will be in Denmark on May 26 - 29, and we would be delighted to meet Danish colleagues interested in aging and longevity studies.

If you are one of them, please contact us at:

gavrilov@longevity-science.org

This is our first trip to Denmark, but we have some prior experience of giving invited lectures in Canada, France, Australia, England, Germany, Japan, Italy, Belgium, Netherlands, Russia, Malaysia, and of course in the United States:

http://longevity-science.org/invited_talks.html

We would be glad to find some people in Denmark interested in aging and longevity studies for possible contacts.

We are invited to REVES meeting on 'Reducing Gaps in Health Expectancy' in Copenhagen, starting on May 26 and until May 29 (please see conference program attached below).

Looking forward to hear from you!

Kind regards,

-- Leonid Gavrilov, Ph.D.:
http://longevity-science.org/CV-gavrilov.htm

-- Natalia Gavrilova, Ph.D.:
http://longevity-science.org/CV-gavrilova.htm

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The 21st REVES conference in Copenhagen 2009

Programme

26 May
Optional training session, 10.00‐15.00
Software for multistate calculations: Hands on SAS session for CI estimation; Bayesian method for HE calculation

Conference 27 - 29 May: Reducing gaps in health expectancy

Except for the concept and methods session (session 5), the presenters will be given 20 minutes each (including discussion).

27 May
8.00‐9.00 Registration
9.00‐9.15 Welcome remarks
9.15‐10.45 Session 1: Harmonization and International comparisons
Chair: Y Saito
- C Jagger, JM Robine, H Van Oyen and the EHLEIS team. A comparison of health expectancies in the EU25: results from the EHLEIS project.
- O Ekholm and H Brønnum‐Hansen. Cross‐national comparisons of non‐harmonized Healthy Life Years indicators may lead to more confusion than clarification.
- NK Rasmussen. Cross cultural comparability of questionnaire based data used for health expectancy calculations.
- M Smith and C White. An investigation into the impact of question change on estimates of general health status and healthy life expectancy in the United Kingdom.
10.45‐11.00 Break

11.00‐12.30 Session 2: Gender
Chair: DJH Deeg
- WJ Nusselder. Decomposition of gender differences in Healthy Life Years.
- H Van Oyen, B Cox, JM Robine and C Jagger for the EHEMU‐team. Patterns in gender gaps in the EU.
- L Frova, A Battisti and A Burgio. Are gaps in disability free life expectancies reducing in Italy?
- RS Goyal. Whether the poverty of women in childhood and adult ages affect their health disability status in later years?

12.30‐14.00 Lunch at Simplycooking, CSS

14.00‐15.45 Session 3: Methods – measures, models, simulations
Chair: MD Hayward
- A Andreotti, N Minicuci, P Kowal and S Chatterji. Multidimensional profiles of health status: An application of the grade of membership model to the World Health Survey.
- F Matthews and A van den Hout. The shape of life and healthy life expectancies.
- X Liu, CC Engel, H Kang and KL Gore. Reducing selection bias in analyzing longitudinal health data with high mortality rates.
- SD Grosse, VA Campbell and G Krahn. Disability or desirability‐adjusted life expectancies? How to interpret Health Adjusted Life Expectancies.
- L Cai. Health‐adjusted value of health care spending on the elderly in the United States, 1992‐2002.

15.45‐16.00 Break

16.00‐17.30 Session 4: Projections, forecasts and scenarios
Chair: H Brønnum‐Hansen
- D Banham. Targeting health expectancy gaps in South Australia.
- M Lagergren, M Thorslund and M Parker. Revised projections of the development of LTC costs in Sweden 2005‐ 2040.
- R Matthews, C Jagger and MRC CFAS. Trends in disease and how they will impact on disability in the older population.
- KJ Anstey and the DYNOPTA collaborators. Pooling longitudinal studies of ageing for epidemiological analysis and to model health futures: the DYNOPTA project.

19.0 Conference dinner at “Spiseloppen”, Christiania (Bådsmandsstræde 43, 2.th. 1407, København K)

28 May
9.00‐11.30 Session 5: Basic concepts and methods
Chair: JM Robine
- K Avlund. How to measure disability, the disablement process and early signs of disability
- C Mathers. The disability process and WHO classification systems, past and future
- Discussion
- Break
- F Matthews. Estimation and statistically considerations
- Y Saito. Software overview

11.30‐14.30 Lunch at Statens Museum for Kunst, National Art Gallery (Sølvgade 48‐50, 1307, København K)
14.30‐15.30 George Myers lecture by James W Vaupel
15.30‐15.45 Break

15.45‐17.15 Session 6: Oldest old and healthy aging
Chair: B Jeune

- LA Gavrilov and NS Gavrilova. Physical characteristics at the midlife and survival to age 100: A study of American men.

- H Engberg, A Oksuzyan, B Jeune, JW Vaupel and K Christensen. Healthy aging in Danish centenarians – a 29 year follow‐up of hospitalizations among 40,000 Danes in the 1905 birth cohort.
- T Sarkeala, M Vuorisalmi, A Hervonen and M Jylhä. Functional status among Finnish nonagenarians in 1996‐2007: Vitality 90+ Study, Tampere.
- VM Shkolnikov, EM Andreev, P Demakakos, A Oksuzyan, K Christensen, MA Shkolnikova and JW Vaupel. Patterns of grip strength in Moscow as compared to Denmark and England.

17.15‐17.30 Break

17.30‐18.30 Session 7: Trends I
Chair: F Matthews
- JW Bruggink. Health expectancies in the Netherlands since 1981.
- CH Van Gool, HSJ Picavet, DJH Deeg, MMY de Klerk, WJ Nusselder, MPJ van Boxtel A Wong and N Hoeymans. Trends in late‐life activity limitations: The Dutch population between 1990 and 2007.
- SL Reynolds and EM Crimmins. Trends in the ability to work among the older US working population, 1997‐2007.

29 May

9.00‐10.45 Session 8: Social, ethnic and other differences
Chair: SL Reynolds
- DC Brown, MD Hayward, JK Montez, MM Hidajat and RA Hummer. The significance of education for rectangularization of the survival curve in the United States.
- R Wilkins. The Canadian census mortality follow‐up study: a new resource for the study of socioeconomic disparities health expectancies.
- K Knoops, JW Bruggink and M van den Brakel. Healthy life expectancy and socio‐economical status in the Netherlands.
- A Burlison. Healthy life expectancy in Scotland.
- Z Zimmer, M Wen and T Kaneda. A multi‐level analysis of urban versus rural differences in functional status transition among older Chinese.

10.45‐11.00 Break

11.00‐12.45 Session 9: Risk factors and chronic diseases
Chair: WJ Nusselder
- L Bonneux, M Reuser and F Willekens. Disability trajectories and life style. A longer life in good health is closed by a longer period in more severe disability.
- B Klijs. Contribution of chronic diseases to the burden of disability in the Netherlands.
- R Ham‐Chande. Demographic structures and aging at the MX‐US border: Social and economic effects on health expectancies and care.
- EM León Diaz and M Gómez. Perception of health of older adults, Havana Cuba. Socio‐demographic and health determinants associated by sex.
- N Brouard, M Espagnacq, JF Ravaud and the Tetrafigap group. Life expectancy of tetraplegic spinal cord injured individuals in France: a ten years follow‐up.

12.45‐14.00 Lunch at Simplycooking, CSS

14.00‐15.00 Session 10: Trends II
Chair: R Wilkins
- LH Chen. Disability‐free life expectancy trends in Taiwan: Compression, expansion or dynamic equilibrium.
- SLK Cheung and SFP Yip. Are we heading to the compression of disability? The case of Hong Kong SAR, 1984‐2008.
- I Pool, W Boddington, J Cheung and R Didham. Differential trends in mortality compression: Assessing the antecedents to gaps in health expectancy in New Zealand.


15.00‐15.30 Closing ceremonies

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Key words:
Denmark, Invited Lectures, REVES, Leonid Gavrilov, Natalia Gavrilova, ageing, aging, geriatrics, gerontology, longevity, centenarians


Home:
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Longevity Science: Call to Danish Colleagues
Shorter weblink:
http://tinyurl.com/cqlnp6


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'Science Against Aging' Research Plan -- Invitation to Discussion

See also:
-- 'Books Forum' blog
-- 'Health Studies' blog


Dear All:

You are cordially invited to participate in discussion of a new 'Science Against Aging' Research Plan:

http://longevity-science.org/SCIENCE_AGAINST_AGING_RESEARCH_PLAN.pdf
Shorter weblink:
http://tinyurl.com/df2kvg

The authors of this program wrote:

Please, answer 12 basic questions on the biology of ageing:

1. Why are organisms exposed to progressive and irreversible reduction of physiological functions in the final period of their lives?

2 . Why do life expectancy and speed of aging differ within one species and across species?

3. Why does experimental treatment such as caloric restriction delay a great number of age-related physiological and pathological changes and increase the average and maximum life duration in animals?

4. Do these factors affect aging and age-associated diseases independently from one another?

5. Do age-related changes in the organism increase the exposure to diseases or do diseases develop independently and only later exacerbate the manifestations of aging?

6. What are, in your view, possible points of a scientific breakthrough in research aimed at increase of longevity?

7. At what evolutionary phase did aging arise or, alternatively, has it accompanied life since its inception?

8. Are the aging processes of an organism caused by aging at the cell level?

9. To what extent are aging processes conditioned genetically?

10. Why do species with 'negligible' aging exist?

11. Are reproduction and life expectancy interrelated or independent from each other?

12. What other questions may be crucial for understanding the mechanisms of aging?

The authors of this program also invited to comment on the sections of their Research Plan:

Section 1
Fundamental Mechanisms of Aging. Main Research Areas

Section 2
Genetics of Lifespan and Aging. Main Research Directions

Section 3
Metabolic Aspects of Aging and Longevity. Main Research Directions

Section 4
Immunity and Aging. Main Research Directions

Section 5
Stem Cells and Aging. Main Research Directions

Section 6
Application of Stem Cells in Geriatrics & Gerontology. Main Research Directions

Section 7
Medicated Geroprotection. Main Research Directions

Section 8
Geroprotectors Efficiency Research. Main Research Directions

Section 9
Identification of the Molecular Markers in Aging. Selected Clauses

Section 10
Mathematical Modelling of the Life Span, Longevity and Aging. Main Research Directions

Section 11
Microecology and Aging. Main Research Directions

Section 12
Reproduction and Aging. Selected Research Directions

Section 13
Environmental Influence on Aging. Selected Research Directions

The Word "doc" version of the entire Program is available at:

http://longevity-science.org/SCIENCE_AGAINST_AGING_RESEARCH_PLAN.doc
Shorter weblink:
http://tinyurl.com/c7e358

Please feel free to post your comments and suggestions below by clicking here.


Key words:
Science Against Aging, Fundamental Mechanisms of Aging, Genetics of Lifespan and Aging, Metabolic Aspects of Aging and Longevity, Immunity and Aging, Stem Cells and Aging, Application of Stem Cells in Geriatrics & Gerontology, Medicated Geroprotection, Geroprotectors Efficiency, Molecular Markers in Aging, Mathematical Modelling of the Life Span, Longevity and Aging; Microecology and Aging; Reproduction and Aging; Environmental Influence on Aging


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and
'Science Against Aging' Research Plan -- Invitation to Discussion
Shorter weblink:
http://tinyurl.com/cxhxs8


.

Upcoming Meeting on Life-Extension (SENS) in England, September 2009

See also:
-- 'Books Forum' blog
-- 'Health Studies' blog


Dear All:

Here is an interesting announcement I have got recently about the upcoming meeting on life-extension (SENS) in Cambridge, England, September 3-7, 2009:

My apologies if you receive this email more than once. Please forward it to any colleagues who you feel may be interested.

I am writing to notify you that registration and abstract submission are now open for the fourth Strategies for Engineered Negligible Senescence (SENS) conference, to be held at Queens' College, Cambridge, England on September 3rd-7th 2009. The early registration and abstract submission deadlines are both June 15th. All details, including forms for abstract submission and online registration, are at the conference website:

http://www.mfoundation.org/sens4

The preliminary program already has 35 confirmed speakers, all of them world leaders in their field. As for previous SENS conferences, the emphasis of this meeting is on "applied gerontology" - the design and implementation of biomedical interventions that may, jointly, constitute a comprehensive panel of rejuvenation therapies, sufficient to restore middle-aged or older laboratory animals (and, in due course, humans) to a youthful degree of physiological robustness. The list of sessions and confirmed speakers is as follows:

Making metabolism less harmful:
Vladimir Skulachev, Holly Brown-Borg, Stephen Spindler, Stephen Vatner

Spontaneous regeneration:
Brandon Reines, Jonathan Tilly, Alexandra Stolzing

Eliminating recalcitrant intracellular molecules:
William Sly, Ana Maria Cuervo, John Schloendorn, Claude Wischik, Martin Hetzer

Rejuvenating extracellular material:
Nik Nikitin, Mark Pepys, Sudhir Paul, Mark Noble, Kendall Houk

Novel anti-cancer approaches:
Paul Hallenbeck, Adela Ben-Yakar, Vera Gorbunova, Maria Blasco, David Keefe

Rejuvenating the immune system:
Janko Nikolich-Zugich, Anne de Groot

ES-like cells and cell therapy:
Justin Ichida, Ilham Abuljadayel, Thomas Zwaka, Daniel Kraft, John Sladek, Dan Gazit

Tissue engineering:
Augustinus Bader, Gabor Forgacs

The defeat of aging and its consequences:
Philip Moriarty, Tanya Jones, Leonid Gavrilov

In addition, there will be at least a dozen short talks selected from submitted abstracts, as well as poster sessions each evening. Authors of short talks and posters will, like the invited speakers, be invited to submit a paper summarising their presentation for the proceedings volume, which will be published in the high-impact journal Rejuvenation Research early in 2010.

Please note that registration fees are fully inclusive of accommodation and all meals. Those not requiring accommodation, and journalists wishing to obtain free press passes (not including accommodation) are asked to contact me by email (aubrey@sens.org).

I hope to welcome you to Cambridge in September!

Cheers, Aubrey

Aubrey de Grey
Organiser, SENS4
Chairman and Chief Science Officer, Methuselah Foundation
Editor-in-Chief, Rejuvenation Research

-------------END--------------------


Key words:
SENS, Life-Extension, Aubrey de Grey, rejuvenation research, Leonid Gavrilov, Strategies for Engineered Negligible Senescence, anti-ageing, anti-aging, ageing, aging, longevity


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.

Call to Swedish Colleagues

Greetings,

We will be in Sweden on July 4 - 9, and we would be delighted to meet Swedish colleagues interested in aging, longevity and life extension.

If you are one of them, please contact us at:

gavrilov@longevity-science.org

This is our first trip to Sweden, but we have some prior experience of giving invited lectures in Canada, France, Australia, England, Germany, Japan, Italy, Belgium, Netherlands, Russia, Malaysia, and of course in the United States:

http://longevity-science.org/invited_talks.html

We would be glad to find some people in Sweden interested in aging, longevity and life-extension for possible contacts.

We are invited to a closed scientific meeting on life-extension near Stockholm, starting on evening July 5, and until afternoon of July 8.

As by now we have two open slots for other invited lectures, if somebody is interested:

1. July 4 until evening of July 5; and

2. evening of July 8 until early morning of July 10.

Thank you!

Kind regards,


-- Leonid Gavrilov, Ph.D.:
http://longevity-science.org/CV-gavrilov.htm

-- Natalia Gavrilova, Ph.D.:
http://longevity-science.org/CV-gavrilova.htm

P.S.: Here are our flight details, just in case:

Arrival to Sweden (Arlanda airport):
Friday, July 4, 12:25 PM (afternoon)
Scandinavian Airlines # 556

Departure from Sweden (Arlanda airport):
Thursday, July 10, 10:15 AM (morning)
United Airlines # 9359 Operated by: SCANDINAVIAN -- SK 945

On the evening of July 4th we could be found at Quality Hotel Airport Arlanda (Cederstromsslinga, Arlanda, SE, 19586), Phone: (46) 8 59 51 11 00, E-mail: q.arlanda@choice.se
http://www.qualityarlandastad.com/eng/index.asp

On the evening of July 5th we could be found at Arlanda airport Radisson SkyCity Hotel (P.O. Box 82, SE-190 45, Stockholm-Arlanda),
Phone: +46 (0)8 50 67 4000; Fax: +46 (0)8 50 67 4001
E-mail: sales.skycity.stockholm@radissonsas.com
http://www.skycity.stockholm.radissonsas.com/

On July 6 - 8 we will be at the Castle Ranas Slott (762 96 Ranas; 60 km to the North from Stockholm, tel.0175 747 00; e-mail: info@ranasslott.se,
http://www.ranasslott.se/index.asp/id/1510/lang/1033
This is a confidential, by-invitation-only scientific meeting. However you are most welcome to send us a message there, if you wish to meet us sometime later, starting on evening of July 8, until the evening of July 9. Thanks!



Home:
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and
Call to Swedish Colleagues
Shorter weblink:
http://tinyurl.com/3ufkd3

.

Adult Development and Aging (New Book)

See also:
-- 'Books Forum' blog
-- 'Health Studies' blog


Greetings,

Here is a new book for discussion:

Adult Development and Aging
by Paul A Roodin and William J. Hoyer
(Hardcover - Jan 15, 2008)

Book Description provided by the Publisher (McGraw Hill Higher Education):

The fifth edition of Adult Development and Aging offers professors and students a clear, comprehensive and current account of the salient issues and concerns that dominate the field of Adult Development. After reading this text, students will have a keen understanding of where adult development and aging has been in the past, where it is right now, and where it will be headed in the future.

In Adult Development and Aging, 5e authors William Hoyer and Paul Roodin combine their expertise in teaching and research to provide clear explanations of the awesome, complex unfolding of development during the adult years. The text presents findings derived from theories and ideas about understanding adulthood and aging in an interdisciplinary, process oriented perspective.

Material is organized in terms of the biological, social and cultural contexts in which change occurs during the adult years. Information is presented in the context of young adults growing older in today’s world, informed by research and theory.

Key words:
New books, Adult Development and Aging, Paul Roodin, William Hoyer, McGraw Hill Higher Education, ageing, gerontology


Do you have any comments on this new book?
Post them below by clicking here !

Home:
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Adult Development and Aging (New Book)
Shorter weblink:
http://tinyurl.com/2bzxsx

.

Oxidation: The Cornerstone of Carcinogenesis -- New Book

See also:
-- 'Books Forum' blog
-- 'Health Studies' blog


Greetings,

Here is a new book for discussion:

Oxidation: The Cornerstone of Carcinogenesis.
Oxidation and tobacco smoke carcinogenesis.
A relationship between cause and effect
by John C. Stavridis (Hardcover - Jan 2008)

Book Description provided by the Springer Publisher:

In order to learn oncology, it is necessary to acquire a comprehensive knowledge of molecular biology in carcinogenesis, and then, with this as a background, to consider the principles of the theoretical and clinical basis of the subject. For graduate students who are preparing themselves for the specialty of internal medicine or clinical oncology, and physicians who wish to become proficient in oncology, it is exceedingly difficult to be highly skilled and completely informed in this expanding field of science without a comprehensive text on the subject. This book is unique, due to its collective approach to the key aspects of the interdependency between three entities: oxidative stress, tobacco smoke and carcinogenesis, operating in a cause-effect sequence, in a concise and to the point manner. I hope this book will prove to be a helpful companion to the internist, the oncologist and the research scientist in molecular biology as well as a work of reference for the general practitioner and physician interested in cancer research.


Information about the Author provided by the Springer Publisher:

John C. Stavridis is a medical doctor who studied Medicine at the Military Medical School of Thessaloniki, Greece. He specialized in Internal Medicine at the Evangelismos Medical Centre, Athens, and received his MD and Professorship from the University of Athens Medical School. Following a postdoctoral position as a senior research fellow and registrar at postgraduate Medical School, London University, Hammersmith Hospital, Department of Clinical Hematology, he joined the Hematology Unit at St. Sabbas Anticancer Hospital, Athens, as director. He taught Physiology from 1991-1999 as a head of the Department of Physiology and full professor at the University of Athens Medical School. Since 1999, Prof. Stavridis has been President of the Institute of Biomedical Research and Biotechnology, Athens.

Key words:
New books, aging, ageing, longevity, gerontology, gerontological, geriatrics, geriatric, senescence, anti-aging, anti-ageing, rejuvenation, life-extension, immortality, Oxidation, Carcinogenesis, tobacco smoke, tobacco, John Stavridis, oncology, oxidative stress

Do you have any comments on this new book?
Post them below by clicking here!

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and
Oxidation: The Cornerstone of Carcinogenesis -- New Book
Shorter weblink:


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Immunosenescence (Medical Intelligence Unit) -- New Book

See also:
-- 'Books Forum' blog
-- 'Health Studies' blog


Greetings,

Here is a new book for discussion:

Immunosenescence (Medical Intelligence Unit)
by Graham Pawelec (Hardcover - Jan 2008)

Book Description provided by the Springer Publisher:

Human immunosenescence contributes to morbidity and mortality in later life. The age-associated increasing incidence of cancer and cardiovascular disease plateaus at around 80 years of age in industrialised countries, but death due to infectious disease continues to increase up to 100 years of age and beyond. Understanding the reasons for age-associated alterations to protective immunity in the elderly would facilitate the development of interventions to reconstitute appropriate immune function, increase responsiveness to vaccination and extend healthspan.

The majority of the papers collected in this volume therefore address not only the mechanisms responsible for immune ageing in humans but consider what might be accomplished to redress the erosion of immune competence with age. The first problem facing the gerontologist investigating human ageing is their longevity: most studies are conducted in a cross-sectional manner, in which parameters of interest in elderly cohorts are compared to young controls. However, the ageing trajectories of people now 80 years old, born at the beginning of the 20th century, will have been very different in mostly unidentifiable ways from those born towards the end of that century. These differences include population genetics, nutrition, stress, disease, and of course, medical treatment, all of which make these two populations hardly comparable.

Key words:
New books, aging, ageing, longevity, gerontology, gerontological, geriatrics, geriatric, senescence, anti-aging, anti-ageing, rejuvenation, life-extension, immortality,Immunosenescence, Medical Intelligence Unit, Graham Pawelec, morbidity, mortality, immunity in the elderly, immune function, healthspan, immune competence


Do you have any comments on this new book?
Post them below by clicking here!

Home:
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and
Immunosenescence (Medical Intelligence Unit) -- New Book
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Medical Decisions, Estrogen and Aging -- New Book

See also:
-- 'Books Forum' blog
-- 'Health Studies' blog


Greetings,

Here is a new book for discussion:

Medical Decisions, Estrogen and Aging
by Jay Schulkin (Hardcover - Dec 21, 2007)


Here is a book description provided by the Springer Publisher:

Book Description

The decision making process that underlies ovarian hormone therapy (HT) is fallible. The question is whether or not physicians should suggest; should one take estrogen or progestin or some other combination of related hormones to women during the menopausal period, when women are deciding about whether to go on hormone therapy for diverse reasons. This decision affects many women in this country and around the world, and is an important factor serving to show what forces influence medical decision-making.

Two recent large-scale studies, one here (Womens Health Initiative or WHI) and the other in Great Britain, cast a negative light on the use of hormone therapy. Both have received considerable attention in the media. Thus, the decision for women to go on hormone therapy (HT) remains controversial. There is an historical oscillation of beliefs related in part to expectations of the medicinal value of HT over longer-term use beyond the initial peri-menopausal period. Studies thought to resolve issues surrounding the efficacy of HT were perhaps over-stated. Confusion still permeates the decision making with regard to HT. Over zealous advertising, and exaggerated understanding of the results (negative or positive) undermines patient and physician decision making.

Key words:
New books, aging, ageing, longevity, gerontology, gerontological, geriatrics, geriatric, senescence, ovarian hormone therapy, HT, estrogen, progestin, Womens Health Initiative, WHI, menopause


Do you have any comments on this new book?
Post them below by clicking here!

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Medical Decisions, Estrogen and Aging -- New Book
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.

New Books on Aging, Longevity, Gerontology, Geriatrics, Life-Extension & Anti-Aging Interventions

New Books on Aging and Longevity Studies upcoming in January 2008.
You are most welcome to add new books here yourself if you do know some new interesting books!

See also the list of over 300 new books on Aging & Longevity published in 2007.


Greetings,

Here is the list of new books on aging and longevity, which will be published this month.

The books are listed in reversed chronological order (the most recent books are listed first). To get more information about these books, just click on the titles below:

1. Living Long and Loving It: Achieving a Healthy and Active Lifestyle
by Irvin M. Korr and Rene J. McGovern (Paperback - Jan 31, 2008)

2. Survival: The Survival of the Human Race (Darwin College Lectures)
by Emily Shuckburgh (Paperback - Jan 31, 2008)

3. microRNAs: From Basic Science to Disease Biology
by Sidney Altman, Victor R. Ambros, and Krishnarao Appasani (Hardcover - Jan 31, 2008)

4. Essentials of Geriatric Physical Therapy
by Jennifer M., Ph.D. Bottomley (Hardcover - Jan 31, 2008)

5. Blood Disorders in the Elderly
by Lodovico Balducci, William Ershler, and Giovanni de Gaetano (Hardcover - Jan 31, 2008)

6. Beat Memory Loss: The Complete Guide to Making the Most of Your Memory (Use Your Brain to Beat... S.)
by Rita Carter (Paperback - Jan 30, 2008)

7. Eternal Puppy: Keeping Your Dog Young Forever
by Janice Willard and Marty Becker (Paperback - Jan 30, 2008)

8. The Myth of Generational Conflict: The Family and State in Ageing Societies
by Sara Arber (Paperback - Jan 30, 2008)

9. Continence Care (Essential Clinical Skills for Nurses)
by Florence Mitchell (Paperback - Jan 30, 2008)

10. Smile for Life: Rejuvenation Dentistry and the Art of Wellness
by Gerald P. Curatola (Paperback - Jan 30, 2008)

11. Fatty Acid and Lipotoxicity in Obesity and Diabetes (Novartis Foundation Symposia)
by Novartis Foundation (Hardcover - Jan 28, 2008)

12. You and Your Aging Parent: A Family Guide to Emotional, Social, Health, and Financial Problems
by Barbara Silverstone and Helen Kandel Hyman (Paperback - Jan 28, 2008)

13. Tales of Graceful Aging from the Planet Denial (Thorndike Press Large Print Nonfiction Series)
by Nicole Hollander (Hardcover - Jan 22, 2008) - Large Print

14. Ultra-Longevity: The Seven-step Program for a Younger, Healthier You (Thorndike Large Print Health, Home and Learning)
by Mark Liponis (Hardcover - Jan 22, 2008) - Large Print

15. You, Staying Young: The Owner's Manual for Extending Your Warranty (Thorndike Large Print Health, Home and Learning)
by Mehmet, M.D. Oz and Michael F., M.D. Roizen (Hardcover - Jan 22, 2008) - Large Print

16. Social Policy in Ageing Societies: Britain and Germany Compared
by Gerhard Naegele and Alan Walker (Hardcover - Jan 22, 2008)

17. Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late
by Sinatra, James C., M.D. Roberts, and Martin Zucker (Paperback - Jan 18, 2008)

18. Adult Development and Aging
by Paul A Roodin and William J. Hoyer (Hardcover - Jan 15, 2008)

19. From Belly Fat to Belly Flat: How Your Hormones Are Adding Inches to Your Waist and Subtracting Years from Your Life -- the Medically Proven Way to Reset Your Metabolism and Reshape Your Body
by M.D., C.W. Randolph and Genie James (Paperback - Jan 15, 2008)

20. The Healthy Seniors Cookbook: Ideal Meals and Menus for People Over Sixty (Or Any Age)
by Marilyn McFarlane and Carol Baird (Paperback - Jan 15, 2008)

21. Senior Days: Insightful Tales and No-Nonsense Help from the Frontlines of Eldercare
by Colleen Nicol (Paperback - Jan 15, 2008)

22. Healthy Aging and Longevity: Third International Conference (Annals of the New York Academy of Sciences)
by Noah J. Weller and Suresh I. S. Rattan (Paperback - Jan 14, 2008)

23. The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow
by Phuli Cohan (Hardcover - Jan 14, 2008)

24. The Vitamin D Cure
by James Dowd and Diane Stafford (Hardcover - Jan 14, 2008)

25. Healthy Aging For Dummies (For Dummies (Health & Fitness))
by Brent Agin and Sharon, RN Perkins (Paperback - Jan 10, 2008)

26. The Myth of Alzheimer's: The Story of a Disease, a Doctor, and a New Direction for Aging in the 21st Century
by Whitehouse M.d., Peter J. ph.d, Danny George, and Julie M. Fenster (Audio Cassette - Jan 8, 2008)

27. The Myth of Alzheimer's: What You Aren't Being Told About Today's Most Dreaded Diagnosis
by Peter J. Whitehouse and Daniel George (Hardcover - Jan 8, 2008)

28. Inheritance in Contemporary America: The Social Dimensions of Giving across Generations
by Jacqueline L. Angel (Hardcover - Jan 4, 2008)

29. Human Aging (2nd Edition) (MyDevelopmentKit Series)
by Paul W. Foos and M. Cherie Clark (Hardcover - Jan 1, 2008)

30. The End-of-life Handbook: A Compassionate Guide to Connecting With and Caring for a Dying Loved One
by David B. Feldman, Stephen Andrew Lasher Jr., and Ira Byock (Paperback - Jan 3, 2008)

31. The 30-Minute Celebrity Makeover Miracle: Achieve the Body You've Always Wanted
by Steve Zim and Steve Steinberg (Hardcover - Jan 2, 2008)

32. American Medical Association Guide to Preventing and Treating Heart Disease: Essential Information You and Your Family Need to Know about Having a Healthy Heart
by American Medical Association, Martin S., MD Lipsky, Marla, MD Medelson, and Stephen, MD, MPH Havas (Hardcover - Jan 2, 2008)

33. Changing Course: Navigating Life after Fifty
by William A. Sadler, Ph.D. and James H. Krefft, and Ph.D. (Perfect Paperback - Jan 2, 2008)

34. Have the Time of Your Life in Retirement: The Help-Yourself Guide for a Fun, Fulfilling Retirement
by Dave Brazier (Paperback - Jan 2, 2008)

35. How Not to Look Old: Fast and Effortless Ways to Look 10 Years Younger, 10 Pounds Lighter, 10 Times Better
by Charla Krupp (Hardcover - Jan 2, 2008)

36. Pet Loss and Human Bereavement
by William Kay, Herbert Nieburg, Austin Kutscher, and Ross Grey (Paperback - Jan 2, 2008)

37. The Relief of Imperfection: For Women Who Try Too Hard to Make It All Just Right
by Joan C. Webb (Paperback - Jan 2, 2008)

38. The Age of Miracles: Embracing the New Midlife
by Marianne Williamson (Hardcover - Jan 1, 2008)

39. Ageless Memory: Secrets for Keeping Your Mind Young Forever - From the World's Foremost Memory Expert
by Harry Lorayne (Hardcover - Jan 1, 2008)

40. Alternative Medicine?: A History
by Roberta Bivins (Hardcover - Jan 1, 2008)

41. Naomi's Guide to Aging Gratefully: Facts, Myths, and Good News for Boomers
by Naomi Judd (Paperback - Jan 1, 2008)

42. The Caregiver: A Life With Alzheimer's (The Culture and Politics of Health Care Work)
by Aaron Alterra and Arthur Kleinman (Paperback - Jan 2008)

43. Oxidation: The Cornerstone of Carcinogenesis: Oxidation and tobacco smoke carcinogenesis. A relationship between cause and effect
by John C. Stavridis (Hardcover - Jan 2008)

44. Sunbelt Retirement: The Complete State-By-State Guide to Retiring in the South and West of the United States
by Peter A. Dickinson (Hardcover - Jan 2008)

45. Ten Years Thinner
by Christine Lydon (Hardcover - Jan 2008)

46. Immunosenescence (Medical Intelligence Unit)
by Graham Pawelec (Hardcover - Jan 2008)

47. Textbook of Men's Health and Aging, Second Edition
by Bruno Lunenfeld, Louis J.G. Gooren, Alvaro Morales, and John E. Morley (Hardcover - Dec 26, 2007)

48. Foods That Combat Aging: The Nutritional Way to Stay Healthy Longer
by Deborah Mitchell (Mass Market Paperback - Dec 26, 2007)

49. Medical Decisions, Estrogen and Aging
by Jay Schulkin (Hardcover - Dec 21, 2007)

50. The Official Anti-aging Revolution: Stop the Clock, Time is on Your Side for a Younger, Stronger, Happier You
by Ronald, M.D. Klatz and Robert, M.D., Ph.D. Goldman (Paperback - Dec 20, 2007)

51. Lecture Notes: Elderly Care Medicine (Lecture Notes)
by Claire Nicholl, Jane Wilson, and Stephen Webster (Paperback - Dec 19, 2007)


The same list is repeated below in enhanced version with book images added:

-----------------

Enhanced List with Book Images Provided (where they are available)


1.
Living Long and Loving It: Achieving a Healthy and Active Lifestyle
by Irvin M. Korr and Rene J. McGovern (Paperback - Jan 31, 2008)


2.
Survival: The Survival of the Human Race (Darwin College Lectures)
by Emily Shuckburgh (Paperback - Jan 31, 2008)


3.
microRNAs: From Basic Science to Disease Biology
by Sidney Altman, Victor R. Ambros, and Krishnarao Appasani (Hardcover - Jan 31, 2008)


4.
Essentials of Geriatric Physical Therapy
by Jennifer M., Ph.D. Bottomley (Hardcover - Jan 31, 2008)

5.
Blood Disorders in the Elderly
by Lodovico Balducci, William Ershler, and Giovanni de Gaetano (Hardcover - Jan 31, 2008)


6.
Beat Memory Loss: The Complete Guide to Making the Most of Your Memory (Use Your Brain to Beat... S.)
by Rita Carter (Paperback - Jan 30, 2008)


7.
Eternal Puppy: Keeping Your Dog Young Forever
by Janice Willard and Marty Becker (Paperback - Jan 30, 2008)


8.
The Myth of Generational Conflict: The Family and State in Ageing Societies
by Sara Arber (Paperback - Jan 30, 2008)

9.
Continence Care (Essential Clinical Skills for Nurses)
by Florence Mitchell (Paperback - Jan 30, 2008)


10.
Smile for Life: Rejuvenation Dentistry and the Art of Wellness
by Gerald P. Curatola (Paperback - Jan 30, 2008)


11.
Fatty Acid and Lipotoxicity in Obesity and Diabetes (Novartis Foundation Symposia)
by Novartis Foundation (Hardcover - Jan 28, 2008)


12.
You and Your Aging Parent: A Family Guide to Emotional, Social, Health, and Financial Problems
by Barbara Silverstone and Helen Kandel Hyman (Paperback - Jan 28, 2008)


13.
Tales of Graceful Aging from the Planet Denial (Thorndike Press Large Print Nonfiction Series)
by Nicole Hollander (Hardcover - Jan 22, 2008) - Large Print


14.
Ultra-Longevity: The Seven-step Program for a Younger, Healthier You (Thorndike Large Print Health, Home and Learning)
by Mark Liponis (Hardcover - Jan 22, 2008) - Large Print


15.
You, Staying Young: The Owner's Manual for Extending Your Warranty (Thorndike Large Print Health, Home and Learning)
by Mehmet, M.D. Oz and Michael F., M.D. Roizen (Hardcover - Jan 22, 2008) - Large Print

16.
Social Policy in Ageing Societies: Britain and Germany Compared
by Gerhard Naegele and Alan Walker (Hardcover - Jan 22, 2008)

17.
Reverse Heart Disease Now: Stop Deadly Cardiovascular Plaque Before It's Too Late
by Sinatra, James C., M.D. Roberts, and Martin Zucker (Paperback - Jan 18, 2008)


18.
Adult Development and Aging
by Paul A Roodin and William J. Hoyer (Hardcover - Jan 15, 2008)

19.
From Belly Fat to Belly Flat: How Your Hormones Are Adding Inches to Your Waist and Subtracting Years from Your Life -- the Medically Proven Way to Reset Your Metabolism and Reshape Your Body
by M.D., C.W. Randolph and Genie James (Paperback - Jan 15, 2008)


20.
The Healthy Seniors Cookbook: Ideal Meals and Menus for People Over Sixty (Or Any Age)
by Marilyn McFarlane and Carol Baird (Paperback - Jan 15, 2008)


21.
Senior Days: Insightful Tales and No-Nonsense Help from the Frontlines of Eldercare
by Colleen Nicol (Paperback - Jan 15, 2008)


22.
Healthy Aging and Longevity: Third International Conference (Annals of the New York Academy of Sciences)
by Noah J. Weller and Suresh I. S. Rattan (Paperback - Jan 14, 2008)


23.
The Natural Hormone Makeover: 10 Steps to Rejuvenate Your Health and Rediscover Your Inner Glow
by Phuli Cohan (Hardcover - Jan 14, 2008)


24.
The Vitamin D Cure
by James Dowd and Diane Stafford (Hardcover - Jan 14, 2008)


25.
Healthy Aging For Dummies (For Dummies (Health & Fitness))
by Brent Agin and Sharon, RN Perkins (Paperback - Jan 10, 2008)


26.
The Myth of Alzheimer's: The Story of a Disease, a Doctor, and a New Direction for Aging in the 21st Century
by Whitehouse M.d., Peter J. ph.d, Danny George, and Julie M. Fenster (Audio Cassette - Jan 8, 2008)


27.
The Myth of Alzheimer's: What You Aren't Being Told About Today's Most Dreaded Diagnosis
by Peter J. Whitehouse and Daniel George (Hardcover - Jan 8, 2008)


28.
Inheritance in Contemporary America: The Social Dimensions of Giving across Generations
by Jacqueline L. Angel (Hardcover - Jan 4, 2008)


29.
Human Aging (2nd Edition) (MyDevelopmentKit Series)
by Paul W. Foos and M. Cherie Clark (Hardcover - Jan 1, 2008)


30.
The End-of-life Handbook: A Compassionate Guide to Connecting With and Caring for a Dying Loved One
by David B. Feldman, Stephen Andrew Lasher Jr., and Ira Byock (Paperback - Jan 3, 2008)


31.
The 30-Minute Celebrity Makeover Miracle: Achieve the Body You've Always Wanted
by Steve Zim and Steve Steinberg (Hardcover - Jan 2, 2008)


32.
American Medical Association Guide to Preventing and Treating Heart Disease: Essential Information You and Your Family Need to Know about Having a Healthy Heart
by American Medical Association, Martin S., MD Lipsky, Marla, MD Medelson, and Stephen, MD, MPH Havas (Hardcover - Jan 2, 2008)


33.
Changing Course: Navigating Life after Fifty
by William A. Sadler, Ph.D. and James H. Krefft, and Ph.D. (Perfect Paperback - Jan 2, 2008)


34.
Have the Time of Your Life in Retirement: The Help-Yourself Guide for a Fun, Fulfilling Retirement
by Dave Brazier (Paperback - Jan 2, 2008)


35.
How Not to Look Old: Fast and Effortless Ways to Look 10 Years Younger, 10 Pounds Lighter, 10 Times Better
by Charla Krupp (Hardcover - Jan 2, 2008)


36.
Pet Loss and Human Bereavement
by William Kay, Herbert Nieburg, Austin Kutscher, and Ross Grey (Paperback - Jan 2, 2008)


37.
The Relief of Imperfection: For Women Who Try Too Hard to Make It All Just Right
by Joan C. Webb (Paperback - Jan 2, 2008)


38.
The Age of Miracles: Embracing the New Midlife
by Marianne Williamson (Hardcover - Jan 1, 2008)


39.
Ageless Memory: Secrets for Keeping Your Mind Young Forever - From the World's Foremost Memory Expert
by Harry Lorayne (Hardcover - Jan 1, 2008)


40.
Alternative Medicine?: A History
by Roberta Bivins (Hardcover - Jan 1, 2008)


41.
Naomi's Guide to Aging Gratefully: Facts, Myths, and Good News for Boomers
by Naomi Judd (Paperback - Jan 1, 2008)


42.
The Caregiver: A Life With Alzheimer's (The Culture and Politics of Health Care Work)
by Aaron Alterra and Arthur Kleinman (Paperback - Jan 2008)


43.
Oxidation: The Cornerstone of Carcinogenesis: Oxidation and tobacco smoke carcinogenesis. A relationship between cause and effect
by John C. Stavridis (Hardcover - Jan 2008)


44.
Sunbelt Retirement: The Complete State-By-State Guide to Retiring in the South and West of the United States
by Peter A. Dickinson (Hardcover - Jan 2008)

45.
Ten Years Thinner
by Christine Lydon (Hardcover - Jan 2008)


46.
Immunosenescence (Medical Intelligence Unit)
by Graham Pawelec (Hardcover - Jan 2008)


47.
Textbook of Men's Health and Aging, Second Edition
by Bruno Lunenfeld, Louis J.G. Gooren, Alvaro Morales, and John E. Morley (Hardcover - Dec 26, 2007)


48.
Foods That Combat Aging: The Nutritional Way to Stay Healthy Longer
by Deborah Mitchell (Mass Market Paperback - Dec 26, 2007)


49.
Medical Decisions, Estrogen and Aging
by Jay Schulkin (Hardcover - Dec 21, 2007)


50.
The Official Anti-aging Revolution: Stop the Clock, Time is on Your Side for a Younger, Stronger, Happier You
by Ronald, M.D. Klatz and Robert, M.D., Ph.D. Goldman (Paperback - Dec 20, 2007)

51.
Lecture Notes: Elderly Care Medicine (Lecture Notes)
by Claire Nicholl, Jane Wilson, and Stephen Webster (Paperback - Dec 19, 2007)


If you do know some new books that should be added to this list, please feel free to add them here!

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